Causes: Acromegaly occurs when the pituitary gland, a small hormone-making structure in the brain, produces too much growth hormone for a long period of time. This hormone normally regulates the ...

2 Most will agree that these goals are probably achieved best by normalizing secretion of growth hormone and insulin-like growth factor 1 (IGF-1) and that the sequelae of acromegaly are serious ...

But as the years went on, he began to notice his body changing in unusual ways: His head grew so much that he needed a larger helmet, and his hands became so big he had to have his wedding ring ...

Acromegaly is a hormonal disorder that arises from the excessive secretion of growth hormone (GH), typically due to a benign tumor on the pituitary gland known as a pituitary adenoma. This ...

When Ray Kohn started feeling pain in his knees and elbows in 2015, he attributed it to his work as a stunt driver and mechanic. But as the years went on, he began to notice his body changing in ...

A majority (nearly 75%) of patients with acromegaly will have a pituitary macroadenoma (>10 mm) at the time of diagnosis, giving rise to the complications of mass effect: headache, visual loss, and ...

The following is a summary of “Paradoxical GH response at OGTT does not predict Pasireotide efficacy but matters for glucose metabolism,” published in the January 2025 issue of Endocrinology by Occhi ...

Acromegaly (Greek-enlargements of the extremities) is a hormonal disorder resulting from excessive production of the growth hormone by the pituitary gland after puberty, often referred as gigantism.

Acromegaly Overview Acromegaly is a rare, slowly progressive, acquired disorder that affects adults. The pituitary gland produces too much growth hormone (GH). The pituitary gland is a small gland ...

Second Lead Pipeline Program Announced: MAR002 for the Treatment of Acromegaly MAR002 is a potential first-in-class anti-growth hormone receptor (GHR) antibody being developed for acromegaly.