Over the past decade, important progress in the treatment options for acromegaly has been made, which required an update of the 'Cortina criteria for cure' described in a consensus statement of ...

But as the years went on, he began to notice his body changing in unusual ways: His head grew so much that he needed a larger helmet, and his hands became so big he had to have his wedding ring ...

Symptoms: Symptoms of acromegaly usually begin sometime after puberty, most commonly between the ages of 40 and 50. The disease causes a person's bones to enlarge — most notably, in the hands ...

Acromegaly is a hormonal condition that occurs ... Other hallmark symptoms include the embossed lines in the head, large hands and growth between the teeth — all symptoms that Yogi-Morren ...

Almost all the patients with acromegaly have acral and soft tissue overgrowth, skin thickening leading to skin tags and swollen hands and feet, coarse facial features, prognathism, interdental ...

Biochemical control of acromegaly in noncured patients is usually defined as serum growth hormone (GH) levels <2.0 µg/l, plus normal-for-age serum levels of insulin-like growth factor I (IGF-I).