G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research.

The ability to regulate blood sugar is essential to our health. When beta cells first recognize higher glucose levels, they depolarize to trigger an increase in intracellular calcium and the rapid ...

and this stimulates cells to take up glucose, an essential step in energy homeostasis. In contrast, alpha cells secrete glucagon in response to decreased blood glucose levels, and this hormone ...