G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research.

A new study has uncovered a critical role for the enzyme Glucose-6-phosphatase 2 (G6PC2 ... influences glucagon secretion in pancreatic alpha (α) cells, a process crucial for maintaining healthy ...

and this stimulates cells to take up glucose, an essential step in energy homeostasis. In contrast, alpha cells secrete glucagon in response to decreased blood glucose levels, and this hormone ...