A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating ...

They also show that models learned from nonsynonymous mutations and from out-of-frame sequences are different, prompting new questions about germinal center function. Strengths of the study include an ...

The H5N1 avian influenza virus is mutating to evade immune defenses in mammals following prior infection or vaccination.

Successful high-affinity B cells can proliferate under special conditions that reduce the risk of mutation. Capturing this ...

New computational modeling of avian influenza variants' immunoprotein interactions—developed by a research team at the ...

Germinal centers are machines of rapid evolution. Germinal centers are tiny clusters in the lymph nodes that refine antibodies through proliferation and mutation to create high-affinity B cells that ...

New computational modeling of avian influenza variants’ immunoprotein interactions – developed by a research team at the University of North Carolina at Charlotte – reveals the H5N1 influenza virus is ...

Galux Inc., a South Korean startup specializing in AI-driven protein therapeutics design, has published a study showcasing ...

Complementing its antibody offerings, BosterBio provides a range of ELISA kits designed for quantitative detection of ...