Atherosclerosis involves multiple processes including endothelial dysfunction, inflammation, vascular proliferation and matrix alteration. Vascular proliferation contributes to the pathobiology of ...

Atherosclerosis, or the buildup of plaque in the arteries, develops when low-density lipoprotein cholesterol (LDL-C) enters the blood vessel walls through dysfunctional endothelial cells (EC ...

A key process in atherosclerosis is the endothelial-to-mesenchymal transition (EndMT), which involves the transformation of endothelial cells into mesenchymal cells, contributing to plaque ...

A key process in atherosclerosis is the endothelial-to-mesenchymal transition (EndMT), which involves the transformation of endothelial cells into mesenchymal cells, contributing to plaque ...

Importantly, however, most of the data pointing to the role of autoimmunity in atherosclerosis comes from studies in transgenic mice. Human atherosclerosis is a complex disorder with a complex ...

Laminar shear stress due to blood flow is a principal regulator of systemic endothelial cell gene expression, morphology, and the production of soluble mediators. Its importance is highlighted by ...

Atherosclerosis, or the buildup of plaque in the arteries, develops when low-density lipoprotein cholesterol (LDL-C) enters the blood vessel walls through dysfunctional endothelial cells (EC ...

Atherosclerosis is a chronic, systemic, inflammatory and metabolic disease and pathologic process characterized by the accumulation of cholesterol and calcium plaque within the arterial wall.