4). Protease digestion or heat treatment abrogated the chemokinetic activity of BMCM, and pretreating T cells with pertussis toxin or antibody against CXCR4 caused an inhibition of bi-directional ...

"This did indeed lead to a significant reduction in CD8 + T cell migration into atherosclerosis plaques," affirms Duchêne, "suggesting that the CXCL12–CXCR4 signaling pathway plays a key role ...

Importantly, the interaction between CXCR4 and its ligand SDF-1 is involved in various disease conditions, such as cancer cell metastasis, leukemia cell proliferation, rheumatoid arthritis and ...

"This did indeed lead to a significant reduction in CD8+ T cell migration into atherosclerosis plaques," affirms Duchêne, "suggesting that the CXCL12-CXCR4 signaling pathway plays a key role in ...