Ostwald and MacLennan isolated seven proteins from an extract of rabbit skeletal muscle sarcoplasmic reticulum, and when they measured the calcium binding activity, only one protein showed a high ...

S100A8, S100A9, and S100A12 are calcium-binding proteins expressed in the cytoplasm of phagocytes. They are rapidly secreted by activated monocytes or neutrophils, which are abundant in inflamed ...