点击蓝字关注我们【导读】免疫检查点阻断疗法（ICB）给癌症治疗带来了革命性的变化，但治疗反应却具有高度异质性，这凸显了开发预测性生物标志物和克服ICB耐药性的必要性。2025年3月17日，中国医学科学院肿瘤医院的研究团队在期刊《Signal ...

S100A8, S100A9, and S100A12 are calcium-binding proteins expressed in the cytoplasm of phagocytes. They are rapidly secreted by activated monocytes or neutrophils, which are abundant in inflamed ...

Ostwald and MacLennan isolated seven proteins from an extract of rabbit skeletal muscle sarcoplasmic reticulum, and when they measured the calcium binding activity, only one protein showed a high ...

Furthermore, three upregulated genes (spectrin repeat containing nuclear envelope protein 2 [SYNE2], S100 calcium binding ...