In humans, heart injury leads to the formation of scar tissue and cardiomyocyte hypertrophy, but the heart does not regenerate. In the December 13 Science, Kenneth Poss and colleagues, at Harvard ...

Cardiac hypertrophy is an adaptive or maladaptive response to stress caused by changes in pressure or volume, which results in an increase in cardiomyocyte size. Cardiac hypertrophy can be classified ...

and we aim to find ways to promote cardiomyocyte renewal after a myocardial infarction. We are also interested in finding treatments that inhibit pathological cardiac remodelling: hypertrophy ...