Chromatin, the mix of DNA and protein that houses each cell's genome, is more resilient to aging than previously thought, suggests a study published in the Journal of the American Chemical Society by ...

The chromatin landscape is a key aspect of epigenetic regulation in eukaryotes. Old histones are recycled during DNA replication, therefore providing a blueprint for the duplication of their ...

The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

New AI model takes minutes rather than days to predict how a specific DNA sequence will arrange itself in the cell nucleus.

MIT chemists use generative AI to predict 3D genomic structures quickly, a process far faster than current methods.

Although the genetic sequence is the same in every cell in the body, only a subset of those genes is expressed by each cell.

cfDNA coverage shows an inverse relationship with both chromatin accessibility and gene expression levels, Using this relationship and machine learning identify patients with cancer.

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

We specialize in high throughput top down liquid chromatography-mass spectrometry. This allows us to study chromatin biology with proteoform level specificity and observe quantitative changes to ...