By reexamining 3D images used to map the connections between brain cells, researchers are uncovering new information about a small, elusive, and often overlooked cellular appendage.

Dysfunctions of the tiny cell processes (primary cilia) of the pancreatic beta cells could be a cause of type 2 diabetes.

In her lab at Washington University in St. Louis, endocrinologist Jing Hughes studies a peculiar structure that sticks out of the surfaces of human pancreatic islet cells: the primary cilium. The ...

But scientists, starting with Alexander Kowalevsky had reported the presence of single (nonmotile) cilia in a variety of vertebrate cells (Kowalevsky 1867). These solitary and apparently ...

The goblet cells secrete mucin proteins in a matrix composed of water, complex sugars, salts which form the mucus. This matrix is distributed evenly on the surface of the epithelium by the ...

Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the ...

Inside the human airway, a certain cell type reigns supreme: multiciliated cells, decorated with dozens of hair-like cilia all beating in tandem. These cells are responsible for clearing out foreign ...

but this requires that all cilia in a tissue orient the same way. Earlier studies indicated that both planar cell polarity (PCP) signalling and cilia-generated fluid flows could influence ciliary ...

The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.

hair-like organelle protruding from the cell surface that transmits cellular signals. Cilia are important for regulating cellular processes, but because of their small size and number, it has been ...