Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

Jianmin Yin. In a separate study published in Angiogenesis, the team examined the role of contractile forces regulated by the proteins Heg1 and Ccm1. "We discovered that these contractile forces ...

Proteins are biopolymers of amino acids (polypeptides), joined by peptide bonds, that are generated by ribosomes. The amino acid sequence, encoded by its gene, determines a protein’s structure ...

nucleic acid (DNA or RNA), and a tail. The tail includes a collar (covered with contractile proteins for the most elaborated bacteriophages, such as the T2 and T4 phages) and ending by tail fibers ...

Generally, training-induced adaptations in skeletal muscle are seen as changes in contractile proteins, mitochondrial function, metabolic regulation, intracellular signalling, transcriptional ...

Our discovery will further boost the development of drugs that wake up hibernating proteins in the respiratory ... often develop contractile weakness of the diaphragm muscle.