C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic ...

For all six proteins, three 'loop' regions are most important for sequence specific DNA binding. The first of these is a segment between the first two strands of the Ig-fold, referred to as the A ...

(a, b) Live-cell single-molecule imaging of the fully assembled SWI/SNF chromatin remodeler complex reveals distinct modes of ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

The team initially set out to study another replication machinery protein, single-stranded DNA-binding protein, and its interaction with DNA polymerase. However, they first needed to establish how the ...

The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...

RNase H is an enzyme involved in genome maintenance, and breaks down RNA in RNA/DNA hybrids in the motor. The slower RNase H binding occurs, the longer the pauses in motion, which is what leads to ...