One of the major constituents of the cell-adhesion complex in epithelial cells is E-cadherin, a transmembrane protein involved in homotypic cell–cell adhesion. E-cadherin exerts a potent ...

These physical signals are determined by the strength of intercellular contacts, the E-cadherin junctions. Moreover, they showed that cells are extruded either apically or basally into the tissue ...

Epidermal growth factor receptor (EGFR) is a major driver of cancer dissemination and target for anti-cancer therapies but ...