Endothelial dysfunction is one manifestation of the many changes induced in the arterial wall by the metabolic abnormalities accompanying diabetes and insulin resistance. In type 1 diabetes ...

Here we report that activation of poly(ADP-ribose) polymerase (PARP) is an important factor in the pathogenesis of endothelial dysfunction in diabetes. Destruction of islet cells with ...

Atherosclerosis cardiovascular disease (ASCVD)-related mortality is higher in patients with lupus nephritis (LN) compared ...

Atherosclerosis involves multiple processes including endothelial dysfunction, inflammation, vascular proliferation and matrix alteration. Vascular proliferation contributes to the pathobiology of ...

Early dysfunction of the endothelial/blood-brain barrier (BBB) is involved in the pathogenesis of cerebral small vessel disease (SVD), which is a contributor to about 50% of dementias.

Decrease endothelial permeability, gap junctions, endothelial dysfunction and improve endothelial repair: aged garlic. Increase NO, reduce A-II effects, increase EPC's, BP control, reduce ...

PTSD significantly impacts cardiovascular health in women with HIV. Screening and treatment could reduce cardiovascular risk.

A history of migraine, with or without aura, was a significant risk factor for open-angle glaucoma onset among a cohort of ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

Following the devastating fires that swept through Los Angeles in January, concerns are on the rise about the long-term health impacts of smoke inhalation.