However, the effect of inflamed endothelial exosomes on the function of macrophages (Mϕ) is poorly defined. This study aims to unravel how exosomes derived from tumor necrosis factor-α ...

Instead, they are taken up by monocyte/macrophages accessible from the circulation, and they bind to and are internalized by endothelial cells. Although endothelial cells in many organs show ...

Three isoforms of nitric oxide synthase (NOS) have been identified: the endothelial isoform (eNOS), neuronal isoform (nNOS), and macrophage or inducible isoform (iNOS). All three NOS isoforms play ...

and also recruit other cell types including lymphatic cells and the endothelial cells required for the development of a blood supply. It has been repeatedly seen that macrophages form a significant ...

Macrophages play this role through the elaboration of angiogenic growth factors. Vascular endothelial growth factor (VEGF) family and platelet derived growth factor C (PDGF-CC) are important for ...

More information: Anna E. Williamson et al, Discovery of an embryonically derived bipotent population of ...

on microvascular disease with apoptosis of microvascular endothelial cells (MVECs) and on fibroblast activation with myofibroblast differentiation and accumulation of extracellular matrix were ...

Localisation of adenoma macrophage chemoattractant protein 1 (MCP-1) and COX-2 were determined by immunohistochemistry. The effects of MCP-1, in the presence or absence of celecoxib, on COX-2 ...