By 1972, Harman recognized the dominant role of mitochondria in the generation of intracellular reactive oxygen species (ROS) and revamped his proposal into the mitochondrial free radical theory ...

There is also a theory that free radical buildup explains the aging process, known as the “free radical theory of aging.” Proponents argue that as the body ages, it accumulates free radicals.

Medically reviewed by Marla Anderson, MD Free radicals are highly reactive and unstable molecules that are made by the body ...

Harman hypothesized that these compounds, which chemists call free radicals, react with cellular components, causing damage that over time leads to aging. In the 1970s he expanded on this theory ...

Free radicals play an important role in oxygen-dependent (aerobic) living systems. They are an important component in cell respiration and other vital cellular processes, but are also involved in ...

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Like vitamin E, vitamin C is considered important in repairing free radicals and preventing them from becoming cancerous or accelerating the aging process. Since vitamin C is most prevalent in the ...