Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a rapidly increasing global prevalence. It is primarily ...

leading to an increase in blood glucose (chronic hyperglycaemia). Since skeletal muscle is the tissue that uses the most glucose in response to insulin action, it is the most affected tissue by ...

This is confirmed by a new study, which identified PanK4 as a key regulator of energy metabolism in skeletal muscle, regulating glucose uptake and fatty acid oxidation and being activated by ...

Excessive consumption of sugar-sweetened beverages (SSBs) doesn’t just cause obesity — it disrupts metabolism across organs, increasing the risk of diabetes and insulin resistance, according to a ...

fatty acids are the main source of energy in skeletal muscle during rest and mild-intensity exercise. As exercise intensity increases, glucose oxidation surpasses fatty acid oxidation. Other ...

and enhanced utilization of glucose in the tricarboxylic acid (TCA) cycle in skeletal muscle, using metabolic flux analysis ...