In humans, heart injury leads to the formation of scar tissue and cardiomyocyte ... scars in the absence of proliferation. These results provide an interesting model to investigate the molecular ...

The study, titled Cross-Species Comparison Reveals Hmga1 Reduces H3K27me3 Levels to Promote Cardiomyocyte Proliferation and Cardiac Regeneration, was published in Nature Cardiovascular Research.

As a part of the Regenerative Pharmacology Unit of the Drug Research Program, our group aims at discovering new ways to treat heart diseases by investigating the molecular mechanisms of cardiac ...