Indomethacin ER capsule 75mg once a day can be substituted for indomethacin immediate-release capsule 25mg three times a day. There will be significant differences between the 2 dosage regimens in ...

Indomethacin has analgesic ... Acute Flares Use lowest effective dose for shortest duration. Initially 25mg 2–3 times daily. If well tolerated, may increase the daily dose by 25 or 50mg at ...