LPS, also known as endotoxin, is a molecule found in the outer membrane of many different types of bacteria. Through its interaction with TLR4, LPS induces a strong inflammatory reaction in humans.

Macrophages play a critical role in the immune ... fibrosis), steroids (deactivation), IFNγ (fights infections), and LPS (a ...

We report here for the first time that high-fat feeding augments plasma LPS at a concentration sufficient to increase body weight, fasted glycemia, and inflammation. LPS infusion in normal diet ...

Phagocytosis is a fundamental mechanism used by the body to resist pathogens and restore physiological homeostasis. Herein, to identify small molecules with anti-inflammatory properties via ...