Immunostaining of mouse retina with anti-CEP antibodies (left panel) was prominant only for the rod outer segments (OS) and retinyl pigmented epithelium (RPE). As predicted, CEPs are only generated in ...

With further development of 3D differentiation protocols, we are now able to achieve similar results with photoreceptor precursors generated from both mouse and human ESC-derived retinal organoids ...

One of my lab's long-term goals is to elucidate the transcriptional and epigenetic mechanisms regulating retinal progenitor cell proliferation and differentiation, leading to new therapeutic ...

This cross-institutional, multi-methodological study provided a comprehensive analysis of retinal proteins, comparing three ...

More information: Guizhi Guo et al, Disruption of photoreceptor cilia is a critical event in the pathogenesis of retinal degeneration—Insights from N-methyl-N-nitrosourea-induced mouse model ...