Mass spectrometry reveals protein acetylation to be as widespread as phosphorylation. Many of the acetylation sites discovered by Choudhary et al. 2 were on proteins in multisubunit complexes.
The first RIPTAC has just hit the clinic. Learn about this new technology that is being developed by Halda Therapeutics.
the positively charged small proteins that package DNA from chromosomes to form particles small enough to fit into cell nuclei. The site(s) and extent of methylation and acetylation determine ...
Hosted on MSN1mon
Scientists uncover key mechanism linking microtubules and chemotherapy, enhancing cancer drug efficacythe team generated recombinant proteins to restore different stages of the enzymatic reaction that leads to microtubule acetylation. Using high-resolution cryo-electron microscopy (cryo-EM ...
Markers of subclinical heart damage were observed among individuals who smoke cigarettes, even decades after quitting, ...
Hosted on MSN17d
Understanding the role of LSD1 in cellular processes and diseaseIt interacts with various protein complexes, allowing it to serve as both a transcriptional activator and repressor. The intricate modifications of LSD1, including phosphorylation, acetylation ...
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