The study was made possible by a new method the scientists developed—DQGlyco—which allows them to study glycosylation at a much higher scale and resolution than previous studies. Proteins are ...

In eukaryotes, glycosylated proteins are ubiquitous components of extracellular matrices and cellular surfaces. Their oligosaccharide moieties are implicated in a wide range of cell?cell and cell?

Viruses like SARS-CoV-2 use sugar molecules to hide from the immune system, but scientists at Scripps Research have designed ...

Lasker Foundation Website (2009). Ungar, D. Golgi linked protein glycosylation and associated diseases. Seminars in Cell and Developmental Biology 20, 762–769 (2009). Xu, D. & Esko, J.

A new study reveals that gut bacteria influence brain protein modifications via glycosylation. Using a novel technique called DQGlyco, researchers identified over 150,000 glycosylated protein forms, ...

Proteins directed towards the ER undergo homogenous glycosylation, a reaction involving the addition of carbohydrates, which is essential for many therapeutic proteins. The accumulation of ...

This article explores how automation is transforming proteomics by streamlining proteoform analysis, boosting throughput and ...

So when she and colleagues aimed to better characterize the miRNAs involved in glycosylation (the process by which sugary molecules are stuck onto proteins), they weren’t expecting to find any ramping ...

Discovery of a novel O-glycosylation of intracellular proteins: Rabbit muscle cytosolic creatine kinase was found to be O-glucosylated via Ser and Thr residues. Other intracellular proteins, such as ...

Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...