Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

EZH1 is a key regulator of circadian rhythms, stabilizing gene transcription and modifying chromatin to maintain genetic ...

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA—the first step of the process by which an organism's ...

coli. Genetically speaking, it's a bacterium's worst-case scenario: during transcription, newly minted RNA sticks to its DNA template, forming a 3-stranded structure known as an R-loop.

can promote transcription at telomeres.” Telomeres were thought to be transcriptionally silent until several years ago when researchers found that mammalian telomeres, including human ones, are ...

Messenger RNA carries genetic information from DNA in the highly protected ... The journey of mRNA begins in the cell nucleus, where it is synthesized through a process called transcription: Through ...

Using a novel, RNA-based approach, we sought to restore this balance in cancer therapies for patients with PCa. This approach was successful in preclinical models, holding promise for suppressing ...