On illumination, rhodopsin passes through several unstable intermediates to a final mixture of retinal and opsin. One of these intermediates, metarhodopsin II, can be reduced by sodium borohydride ...

Very little is known about the molecular structures of retinal antigens. One possibility is that an immune response may result from a defect in maintaining tolerance for self-antigens, e. g., ...

Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness. The compounds were identified using a virtual screening approach.

At the heart of this issue is the protein rhodopsin, which, due to genetic mutations, often misfolds. This misfolding disrupts its function, leading to retinal cell degeneration. Scientists have ...

Food plays an important role in eye health and can help prevent or alleviate vision problems. Several nutrients have ...

Treatment with bioavailable small-molecule pharmacochaperones targeting the visual receptor rhodopsin offers a promising approach to prevent retinal photoreceptor degeneration caused by inherited ...

The review concludes with Section VIII, with remarks about the future directions of research on retinal guanylate cyclases. The ventral nerve photoreceptor of the horseshoe crab Limulus polyphemus has ...

In retinitis pigmentosa the retina protein rhodopsin is often misfolded due to genetic mutations, causing retinal cells to die off and leading to progressive blindness. Small molecules to correct ...

In retinitis pigmentosa, the retina protein rhodopsin is often misfolded due to genetic mutations, causing retinal cells to die off and leading to progressive blindness. Small molecules to correct ...

Professor Yuki SUDO of Okayama University seeks an innovative form of treatment using rhodopsin, a protein with light-reactive qualities. By extracting it and artificially inserting it into ...

In retinitis pigmentosa, the retina protein rhodopsin is often misfolded due to genetic mutations, causing retinal cells to die off and leading to progressive blindness. Small molecules to correct ...