Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and ...

Transforming Growth Factor Beta (TGF-β) signaling pathways play a crucial role in regulating various biological processes, including cell growth, differentiation, and immune responses.

Effects of the TGF-β family on differentiation Several classes ... the selection and the progression of the differentiation pathways during development. Among these, TGF-β family members have ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Dr. Massagué identified the TGF-β receptors, their mechanism of signal transduction, and the central concept of how this pathway controls cell division and developmental fate. He provided a direct ...