The boundary of each cell is defined by the phospholipid ... Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 282: 2085- 2088 (1998) doi: 10.1006/bcmd.

which leads to mitochondrial damage and a dangerous form of cell death that not only harms the liver but also other organs, including the immune system. There was also increased activity in the TLR4 ...