Mapping the key signaling molecules in biochemical pathways will be central to future drug discovery efforts. Signal transduction describes the process of conversion of external signals ...

Davis, University of Massachusetts Medical School, Howard Hughes Medical Institute. The signal transduction pathways of mitogen-activated protein (MAP) kinases have been actively studied for some time ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...

Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in BMP2 signaling pathways," Cell, 85:489-500 ... If there is one thing that is known about the mechanisms that govern signal ...

Members of the program engage in research aimed at obtaining a mechanistic understanding of signal transduction and cellular regulation, which includes cellular signaling pathways and downstream ...