The 2025 Concacaf Nations League is upon us, and it’s a massive opportunity for the United States, Canada and Mexico to prepare ahead of hosting FIFA World Cup 2026 while giving Panama challenging opponents amidst their qualification journey.

Some late injury news could shake up Mauricio Pochettino's roster ahead of the team's semifinal against Panama

The USMNT is the only side to win the Nations League thus far, having won it in 2021, 2023 and 2024 under previous coach Gregg Berhalter. Elsewhere in the squad, midfielders Tyler Adams and Gio Reyna are back in the mix after lengthy spells out of the team due to injury and fitness concerns.