Causes: Acromegaly occurs when the pituitary gland, a small hormone-making structure in the brain, produces too much growth hormone for a long period of time. This hormone normally regulates the ...

Acromegaly is a hormonal disorder that arises from the excessive secretion of growth hormone (GH), typically due to a benign tumor on the pituitary gland known as a pituitary adenoma. This ...

But as the years went on, he began to notice his body changing in unusual ways: His head grew so much that he needed a larger helmet, and his hands became so big he had to have his wedding ring ...

Both growth hormone deficiency (GHD) and acromegaly, a condition characterized by excess GH, can lead to alterations in bone structure and an increased risk of fractures. Recent research has ...

When Ray Kohn started feeling pain in his knees and elbows in 2015, he attributed it to his work as a stunt driver and mechanic. But as the years went on, he began to notice his body changing in ...

A majority (nearly 75%) of patients with acromegaly will have a pituitary macroadenoma (>10 mm) at the time of diagnosis, giving rise to the complications of mass effect: headache, visual loss, and ...

The following is a summary of “Paradoxical GH response at OGTT does not predict Pasireotide efficacy but matters for glucose metabolism,” published in the January 2025 issue of Endocrinology by Occhi ...

Acromegaly (Greek-enlargements of the extremities) is a hormonal disorder resulting from excessive production of the growth hormone by the pituitary gland after puberty, often referred as gigantism.

Acromegaly Overview Acromegaly is a rare, slowly progressive, acquired disorder that affects adults. The pituitary gland produces too much growth hormone (GH). The pituitary gland is a small gland ...

Second Lead Pipeline Program Announced: MAR002 for the Treatment of Acromegaly MAR002 is a potential first-in-class anti-growth hormone receptor (GHR) antibody being developed for acromegaly.