With its discovery of small molecules that activate RNA methylation, the biotech has broken new ground in epitranscriptomics. This breakthrough positions Chemestmed to advance candidates with the ...

They say that change takes time. Well, that's not the case for RNA. The small biological molecule acts like a switchboard ...

UK biotech MiNA Therapeutics has signed up another big pharma partner for its small activating RNA (saRNA) platform, which upregulates the activity of proteins, with Eli Lilly the latest to get in ...

Figure 1: Epididymal and testicular histology in Tarbp2-/-mice. Figure 3: In situ hybridization and immunohistochemistry of GH1, Tnp2 and Prm2. For histological evaluation, we fixed dissected ...

They say that change takes time. Well, that's not the case for RNA.The small biological molecule acts like a switchboard ...

A study reveals DNA and RNA epigenetics work together as a complementary system for precise gene regulation, crucial for cell ...

the ribozyme can chemically modify other RNA molecules at a specific site and thus influence their function -- for example, activate them or render them recognisable by proteins. Such ...

Mutations in the SOD1 gene account for approximately 20% of familial ALS and 5% of the sporadic ALS cases. A leader in small activating RNA (saRNA) drug development, Ractigen Therapeutics is at the ...

Until now, DNA and RNA epigenetics were studied as independent ... they enable a more effective activation of that gene. On the other hand, if one of these processes is not working correctly ...

When they detect the presence of RNA viruses, they activate interferons through the mitochondrial antiviral signaling (MAVS) pathway. The MAVS protein resides on the outer membrane of a cell's ...

Some of the cell's RNA molecules, researchers found, help regulate antiviral signaling. These signals are part of the intricate coordination of immune responses against virus invasion.

In recent news, pioneer in RNA activation therapeutics MiNA Therapeutics recently announced their positive findings from MTL-CEBPA clinical trial in patients with advanced liver cancer.