This mini-review summarizes the current evidence for the role of macrophage activation and polarization in inflammation and immune response pertinent to interstitial lung disease, specifically ...

This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...

Department of Physiology, State Key Laboratory of Common Mechanism Research for Major Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical ...

Further analysis revealed that hypoxic CD71+ neutrophils expressed an additional gene, ARG1, that caused the immunosuppressive effect. Without ARG1, even hypoxic CD71+ neutrophils did not suppress ...

The hypoxic CD71 + neutrophils had come to acquire ARG1 expression and its immunosuppressive effects, but researchers did not yet know how. Dr. Veglia and team suspected an interplay between ...

The researchers also discovered that when these cells, called macrophages, eat live bacteria it triggers an inflammation response. But when they eat dead bacteria it doesn't. "When phagocytic ...

This important study reveals that disrupting fatty acid metabolism in macrophages significantly restricts the growth of Mycobacterium tuberculosis, showing that impaired lipid processing triggers ...

This study provides useful information by identifying the cell type (macrophages) in synovial tissues involved in the pathogenesis of post-traumatic osteoarthritis (OA) and clarifying distinct ...

real-time RT-PCR was performed to detect mRNA expressions of M2 macrophage markers. AS1517499 treatment suppressed mRNA expression abundance of Arg1, MRC1, Fizz1, and CCL17 in obstructed kidneys ...