A substantial and persuasive body of data now exists that supports the view that integrin alpha V beta 3 plays a critical part in activated macrophage dependent inflammation, osteoclast development, ...

Stroke is a devastating disease for which no clinical treatment exists to regenerate lost tissue. Strategies for brain repair in animal models of stroke include the delivery of drug or cell-based ...

Biological processes were mainly involved in synaptic transmission activities, such as synapse organization, axonogenesis, vesicle organization ... RNA polymerase II distal enhancer sequence-specific ...

LC3 is required for canonical and non-canonical autophagy. Here, the authors uncover LAPTIN, a function of LC3 triggered by integrin LFA1 outside-in signaling, which activates AMPK to drive the co ...

Department of Nuclear Medicine, School of Medicine & Health, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Strasse 22, Munich 81675, Germany Central ...

Department of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an 710032, ...