Feb. 7, 2025 — A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into ...

Department of Chemistry, Sogang University, Seoul 04107, Republic of Korea ...

Hefei National Research Center for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui 230026, China School of Chemistry and Materials Science, University ...

Molecular Biology is the field of biology that studies the composition, structure and interactions of cellular molecules such as nucleic acids and proteins that carry out the biological ...

The molecular dynamic simulations were carried out with the help of the DESMOND tool of the Schrödinger suite. The protein–ligand complexes were placed in an orthorhombic box with a simple point ...

The international team describes their results and the underlying molecular mechanism in Cell Metabolism. Ergothioneine is a natural compound found in certain fungi such as oyster or shiitake ...

Kirsten rat sarcoma (KRAS) is a potent oncogenic driver that results in the downstream hyperactivation of MAPK signaling while simultaneously increasing replication stress (RS) and accumulation of DNA ...

1 H and correlation spectroscopy (COSY) 2D 1 H-1 H nuclear magnetic resonance (NMR) spectra were obtained on a Bruker DRX spectrometer of 300 and 500 MHz. The samples were prepared by dissolving 5 mg ...