Importantly, the interaction between CXCR4 and its ligand SDF-1 is involved in various disease conditions, such as cancer cell metastasis, leukemia cell proliferation, rheumatoid arthritis and ...

Department of Developmental Biology and Genetics, Indian Institute of Science, Bengaluru 560012, India Longevity India, Indian Institute of Science, Bengaluru 560012, India ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

代谢物是健康的关键指标和治疗靶点，但其在妊娠期（人类生殖的关键阶段）的遗传基础仍未被充分探索。我们利用来自无创产前检测的遗传数据，对34,394名中国孕妇的84种代谢物（包括37种氨基酸、24种元素、13种激素和10种维生素）进行了全基因组关联研究， ...

Consistent data indicate that NB tumor microenvironment (TME) is dominated by myeloid cells, with little (but variable) T cell infiltration. The obstacles to lymphocyte infiltration and to their ...

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

With the use of T cell receptor T cells (TCR-T cells) and chimeric antigen receptor T cells (CAR-T cells), T-cell immunotherapy for cancer has advanced significantly in recent years. CAR-T cell ...

There are two main types of lymphocytes, called B cells and T cells. But the kind involved in this type of lymphoma are B cells. These cells make antibodies, which are proteins that help your body ...