The Cancer in Young People in Canada (CYP-C) program is a national, population-based surveillance system studying all children and youth diagnosed with cancer in Canada. CYP-C collects information on ...

Dutasteride and tamsulosin are one of the first-line combination therapies for the management of benign prostatic hyperplasia (BPH). Combination therapy is frequent in BPH patients, due to ...

METHODS: The CYP enzymes responsible for quetiapine metabolite formation were assessed using recombinant expressed CYPs and CYP-selective inhibitors. P-glycoprotein (Pgp) transport was tested in ...

Cytochrome P450 (CYP) enzymes are a large class of heme-thiolate protein superfamily serving the key enzymes in the first-pass metabolism of many foreign substances in humans (Krishna and Shekar, 2005 ...