With recent advances in the development of human Inducible pluripotent stem cell derived cardiomyocytes (iPSC-CMs), novel compounds can be assessed with better disease relevance while more accurately ...

Department of Internal Medicine, Division of Cardiology (N.T.L., N.U.N.N., W.M.E., C.-C.H., I.M.-M., F.X., S.R.A., N.V., N.B., L.E.-F., Q.M.O., A.C.C., M.S.A., S.L ...

The tiny bits of plastic pollution that make their way from the environment into our bodies accumulate at much higher ...

A recent Brazilian study published in Nature Cardiovascular Research has highlighted promising pathways for preventing and ...

A disrupted protein degradation process in heart muscle cells can lead to a range of severe heart diseases. In the case of ...

A new study has identified an enzyme that plays an important role in breaking down unneeded or damaged proteins in the heart -- an important process for maintaining heart health.

This paper highlights the use of SMART in several biological test cases including cellular mechanotransduction, calcium signaling in neurons and cardiomyocytes, and adenosine triphosphate synthesis.

Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques ...

CardioOncology, shows that administration of the SGLT2 inhibitor empagliflozin to pigs receiving anthracyclines preserves ...

EHM allografts restore heart muscle safely, offering a breakthrough in heart failure treatment with no arrhythmia risk.

A team of scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working in collaboration with international partners, has designed a strategy for preventing the cardiotoxic ...

Cardiovascular diseases (CVDs) are the key factors leading to death and disability worldwide. This severe challenge has prompted the scientific research and ...