The heartbeat is carried out by specialized heart muscle cells called cardiomyocytes that can neither divide nor renew themselves. As a result, the loss of a large number of these cells ...

A discovery in cardiac regeneration offers ew hope for the treatment of ischemic heart failure. Published in npj Regenerative ...

The discovery of a novel approach to promote cardiomyocyte proliferation offers new hope for the treatment of ischemic heart failure.

“When the heart cannot replace injured cardiomyocytes with healthy ones, it becomes progressively weaker, a condition leading ...

Adult human hearts possess limited regenerative abilities, so losing cardiomyocytes (CMs) after injury can result in contractile dysfunction and heart failure. In contrast, neonatal mammalian ...

Researchers in the Michael E. DeBakey Department of Surgery at Baylor College of Medicine, the QIMR Berghofer Medical Research Institute in Brisbane, Australia, and collaborating institutions report a ...

More information: Yi-Wei Tsai et al, N-Cadherin promotes cardiac regeneration by potentiating pro-mitotic β-Catenin signaling in cardiomyocytes, Nature Communications (2025). DOI: 10.1038/s41467 ...