Some of these differences include ion channel kinetics, upstroke velocities, structural differences in the contractile machinery, isoform of proteins, and metabolic function. TTCC: T-type calcium ...

However, our phosphoproteomic analysis showed that the majority of the phosphosites that were altered by IPC were related to myocardial contraction, suggesting that IPC exerts part of cardioprotective ...

Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals that make muscles contract are also responsible for transmitting signals in ...

Membrane proteins are proteins found in cell membranes, either at the surface or on intracellular organelles. Integral membrane proteins such as receptors and ion channels span the membrane.

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Once confined to sportsmen and women, high-protein diets are now commonplace – with Paleo, Atkins, Zone and Dukan advocating that people eat large quantities of fish, meat, eggs, nuts and cheese ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Protein design (or protein engineering) is a technique by which proteins with enhanced or novel functional properties are created. Proteins can be engineered by rational design, which typically ...

A disrupted protein degradation process in heart muscle cells can lead to a range of severe heart diseases. In the case of dilated cardiomyopathy, a pathological enlargement of the heart chambers ...