Important insights into the mechanisms behind Fuchs endothelial corneal dystrophy (FECD), a common cause of age-related visual loss, have been revealed in a new study led by UCL researchers.

In 2022, doctors in Japan performed a transplant of iPS cell-derived corneal endothelial cells iPS cell ... including the heart, nerves and blood. In 2022, Keio University performed the world's ...

In this cross section of a cornea in a person with Fuchs' dystrophy, the green rectangles represent endothelial cells. The magenta dots are outgrowths of Descemet's membrane known as guttae.

At the same time, keratic precipitates (Fig. 1A) were seen in 12 eyes as discrete hyperreflective spots attached to the cornea endothelium, and fibrinous membrane (Fig. 1B) were detected in 4 eyes ...