Abstract: Segmenting corneal endothelial cells in conditions like Fuchs endothelial dystrophy (FED) is challenging due to guttae obscuring cell details and complicating imaging. This is further ...

We read with interest the paper by Gain et al, 1 which assessed two distinct techniques to quantify corneal endothelial cell death in donor corneas. A significantly higher rate of cell death was ...

Important insights into the mechanisms behind Fuchs endothelial corneal dystrophy (FECD), a ... series of experiments to understand how this mechanism plays out throughout human development ...

“Alcon is dedicated to developing and delivering innovative treatments for global unmet needs in eye care, including vision-threatening corneal endothelial disease, which affects millions of ...

Corneal edema may occur as a result of poor pump function of the altered corneal endothelium or from elevated IOP due to secondary angle-closure glaucoma. Although the true etiology of ICE ...

using only donor Descemet's membrane with endothelium. However, early adoption by corneal surgeons has been limited (illustrated by graft registry reports: 0.7% all corneal transplants in the USA; 0.4 ...

Descemet Membrane Detachment (DMD), and retraction of the corneal endothelial face near the limbus. 10, 13 This study aimed to evaluate the accuracy and quality of healing of main corneal incisions in ...

The first high resolution structure of an ATP-dependent cation pump of the P-type family ... ATP binding site supports a single site mechanism of regulation. However, uncertainty remains ...

The centers of all corneas were cut using a 6-mm biopsy punch before being placed (endothelium ... mechanism for drugs targeting this challenging area. In this context, AuNPs have emerged as ...

While the soft mechanics and tunable cell interactions facilitated by hydrogels have attracted significant interest in the development of functional hydrogel-based tissue engineering scaffolds, ...