Transgenic animals continue to play an essential role in many aspects of zebrafish research, including the development of disease models. The most widely used system for zebrafish transgenesis is the ...

Site-specific endonucleases that exclusively cut single-stranded DNA have hitherto never been described and constitute a barrier to the development of ssDNA-based technologies. Here the authors ...

When there is a strong suspicion of a deletion that cannot be identified by conventional methods, we often resort to multiplex ligation-dependent probe amplification (MLPA) for detection. Nonetheless, ...

The small study in patients with a rare disorder that causes liver and lung damage showed the potential for precisely targeted infusions. By Gina Kolata Researchers have corrected a disease ...

Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering ...

A research team has identified NEAT1, a long non-coding RNA, as a key player in DNA repair. This discovery links RNA metabolism to genome stability and opens up potential new cancer treatments. Credit ...

The prosecution’s most important piece of evidence is a DNA sample taken from a knife sheath left at the crime scene. Investigators then used investigative genetic genealogy, or IGG, a forensic ...

I was one of the first to spit into a test tube, giving up my DNA forever to learn more about my health and heredity. You know, the ones that promise to connect you with distant relatives you didn ...

School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 211166, China ...

Tubal ligation is a surgical procedure that blocks or removes your fallopian tubes, which carry eggs from the ovaries to the uterus. It's a sterilization (making someone unable to have kids) technique ...

Overall, 24 known PD-associated genes were detected by whole exome sequencing and multiplex ligation-dependent probe amplification (MLPA) from patient samples. The genetic and clinical characteristics ...