DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

But as they age, they accumulate more and more DNA damage. Until now, it has been unclear why the cell's repair mechanisms do not fix the damage. Researchers led by Melina Schuh and Ninadini ...

Human polymerase θ helicase positions DNA microhomologies for double-strand break repair. Nature Structural & Molecular Biology , 2025; DOI: 10.1038/s41594-025-01514-8 Cite This Page : ...

A research team has identified NEAT1, a long non-coding RNA, as a key player in DNA repair. This discovery links RNA metabolism to genome stability and opens up potential new cancer treatments. Credit ...

Their disrupted sleep cycles can lead to a reduced ability to repair oxidative DNA damage, which might, over time, increase their risk of developing serious health issues. In the Canadian study ...

Melatonin intervention linked to borderline significant increase in urinary 8-OH-dG, which is indicator of oxidative DNA damage repair capacity. HealthDay News — For night shift workers, melatonin ...

Credit: Scripps Research A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 mutations. DNA repair proteins function as the body’s ...

This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, constantly finding and reversing damage to our genetic code. Researchers ...

More information: Christopher J. Zerio et al, Human polymerase θ helicase positions DNA microhomologies for double-strand ...