Dendritic localization of the α subunit of Ca 2+ /calmodulin-dependent protein kinase II (αCaMKII) mRNA in CNS neurons requires its 3′ untranslated region (3′UTR). We investigated this ...

In this manuscript, Griesius et al analyze the dendritic integration properties of NDNF and OLM interneurons, and suggest that the supralinear NMDA receptor-dependent synaptic integration may be ...

Methods: We performed immunostaining on human skin and peripheral blood mononuclear cells (PBMCs) and visualized primary cilium. Result and discussion: We show that human dendritic cells (DCs) and LCs ...

Dendritic cells (DCs) are crucial for the initiation and regulation of adaptive immune responses. When encountering immune stimulus such as bacterial and viral infection, parasite invasion and dead ...

The properties of the dendritic tree have important implications for neuronal function. But if dendrites were strictly passive, this would limit their ability to contribute to synaptic integration.

Therefore, researchers from Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Heraklion, Crete, Greece have developed a novel solution, dendritic ANNs, ...

Given the central role of dendritic cells (DCs) in initiating and shaping antiviral T cell responses, it is important to understand how these cells interact with hepatitis viruses and their products, ...

Researchers have identified a unique mitochondrial process in CA2 neurons that supports learning, memory, and social recognition.

The new research reveals a novel mechanism for signal transmission in brain cells and helps answer an open question in neuroscience about how intracellular signals travel over long distances in ...

Virginia Tech neuroscientists have uncovered a mitochondrial process that supports the brain cells critical for learning, ...

A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of ...

引言CAR-T（嵌合抗原受体T细胞）疗法在血液系统恶性肿瘤的治疗中取得了突破性进展。然而，由于实体瘤的肿瘤微环境（TME）高度免疫抑制、肿瘤抗原表达的异质性及T细胞渗透能力受限，CAR-T在实体瘤治疗中面临显著挑战。为克服这些问题，2月7日Nature Medicine的研究报道“CAR-macrophage therapy for HER2-overexpressing ...