Damage to the dorsal striatum impairs the ability to form habits, resulting in an over-reliance on slower and more effortful goal-directed modes of action at the expense of the faster and less ...

These include anterior cingulate cortex (ACC), medial orbitofrontal cortex (OFC) and ventral striatum (VS). Strikingly, these changes are present across a disparate range of underlying pathologies and ...

In the DSM-5, psychiatric diagnoses are made based on self-reported symptoms and clinician-identified signs. Though helpful in choosing potential interventions based ...

Figure 1. The cortico-basal ganglia-thalamo-cortical loop in human brain. The brain areas on the circuit contain: prefrontal cortex (PFC), OFC, premotor cortex (PM), thalamus, striatum (StrD1 and ...