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Physical signals as fate deciders: How mechanical forces extrude cells from tissuesThese physical signals are determined by the strength of intercellular contacts, the E-cadherin junctions. Moreover, they showed that cells are extruded either apically or basally into the tissue ...
One of the major constituents of the cell-adhesion complex in epithelial cells is E-cadherin, a transmembrane protein involved in homotypic cell–cell adhesion. E-cadherin exerts a potent ...
E-cadherin is a transmembrane glycoprotein involved in epithelial cell adhesion. In cancer, downregulation of this protein enhances tumor cell dissociation, thereby increasing the risk of ...
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