One of the major constituents of the cell-adhesion complex in epithelial cells is E-cadherin, a transmembrane protein involved in homotypic cell–cell adhesion. E-cadherin exerts a potent ...

E-cadherin is a transmembrane glycoprotein involved in epithelial cell adhesion. In cancer, downregulation of this protein enhances tumor cell dissociation, thereby increasing the risk of ...

These physical signals are determined by the strength of intercellular contacts, the E-cadherin junctions. Moreover, they showed that cells are extruded either apically or basally into the tissue ...