TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related mortality worldwide. Current treatment modalities are few or ...

Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.

Combined, these findings show that CMA displays a broad targetability on multiple steps of the EMT process and indicate a substantial role of CMA in regulating the stability of pro-metastatic and ...

Notch signaling has been identified as a key regulatory pathway in patterning the endocardium through activation of endothelial-to-mesenchymal transition (EMT) in the atrioventricular canal (AVC) and ...

Numerous studies have delved into asthma’s pathogenesis, among which epithelial mesenchymal transition (EMT) is considered one of the important mechanisms in the pathogenesis of asthma. EMT refers to ...

TABLE 3. A summary of current erosolized liposome formulations targeting EMT-markers in the literature. FIGURE 4. Schematic illustration of the different polymeric NP formulations, with their relative ...

Arginine methyltransferase PRMT7 is associated with human breast cancer metastasis. Endosomal FAK signalling is critical for cancer cell migration. Here we identified the pivotal roles of PRMT7 in ...