Peptides act as signal mediators in the body and are on the rise as therapeutic agents. However, their full potential can ...

Remarkably, this chemistry transforms lysine, a nucleophile, into an electrophilic warhead. We demonstrate its versatility in late-stage peptide diversification, precision protein engineering, and ...

Alkenes - Geometrical isomerism, mechanism of electrophilic addition, addition of hydrogen, halogens, water, hydrogen halides (Markownikoffs and peroxide effect), Ozonolysis and polymerization.

Division of Physiological Chemistry and Metabolism, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-0011, Japan Laboratory of Metabolomics, RIKEN Center for Integrative ...

Alkenes - Geometrical isomerism, mechanism of electrophilic addition, addition of hydrogen, halogens, water, hydrogen halides (Markownikoffs and peroxide effect), Ozonolysis and polymerization.

Adding fluorine to drug molecules can be tricky, but is often worthwhile. Rachel Brazil talks to the chemists trying to tame ...

Aging is the progressive loss of organ and tissue function over time. Growing older is positively linked to cognitive and biological degeneration such as physical frailty, psychological impairment, ...

TCM regulates autophagy through these pathways and alleviates DOX-induced cardiotoxicity. In addition to these mechanisms, whether non-coding RNAs regulate autophagy, epigenetics of autophagy, protein ...